
Andrew Kruse

Research in my lab aims to elucidate the molecular basis of transmembrane signaling through the use of biochemistry, pharmacological studies, and structural biology. We are particularly interested in signaling pathways with connections to human health and disease, including G protein-coupled receptors and other transmembrane receptors. In the long term, we aim to leverage a detailed molecular understanding of these pathways to facilitate the development of new and better therapeutics.
Anthony Banks

Victor Calvillo-Miranda

Victor received his B.S. in Microbiology with a minor in Biochemistry from the University in Arizona where he worked under the supervision of Dr. May Khanna in identifying small molecule modulators of TDP43 and Malat1, both implicated in neurodegenerative diseases, using in silico docking and biophysical binding assays. After graduating from the UA, Victor joined the Chemical Biology program in 2020 and joined the Kruse lab in 2021. In his spare time, he enjoys spending time with his partner and dogs, playing chess, and spending time at the beach.
Clare Canavan

Josh Cofsky

Josh (B.S., Molecular Biophysics & Biochemistry, Yale, 2015; Ph.D., Molecular & Cell Biology, UC Berkeley, 2021) completed his doctoral work in the labs of Jennifer Doudna and John Kuriyan, where he studied how protein and nucleic acid conformational dynamics enable the function of CRISPR-associated enzymes in bacterial immunity and genome editing applications. In 2022, he began his postdoc in the Kruse lab, where he is using biochemistry and structural biology to probe bacterial membrane protein function. Outside of lab, Josh likes Baroque music, climbing on real and fake rocks, and sleeping in tents.
Morgan Gilman

Edward Harvey

Joe Hurley

Lauren Litzau

Genevieve Nemeth

Genevieve grew up in Chicago and went to college in NYC at Barnard College, where she received a B.A. in Chemistry. At Barnard, she wrote her undergraduate thesis in electrochemistry and surface chemistry based on the molecular and physical interactions of biological selenium and gold. After college, she moved to Boston and in January 2021 joined the Kruse Lab, where she looks to gain biochemical experience such as growing cells, electron microscopy, and crystallography. In her free time, Genevieve enjoys biking, reading, camping, making zines, and making dumplings.
James Osei-Owusu

James received his Ph.D. in Cellular and Molecular Physiology from Johns Hopkins School of
Medicine under the supervision of Dr. Zhaozhu Qiu. His thesis work focused on structure-
function characterization of a novel proton-activated chloride channel (PAC). James likes to hike
and play soccer in his spare time. He joined the Kruse Lab in November 2021.
Irina Shlosman

Meredith Skiba

Jeffrey Smith

Jeffrey is from Washington State and attended the University of Washington for undergraduate. There he joined the laboratory of Charles Chavkin, studying how the kappa opioid receptor regulates stress and addiction. He subsequently matriculated in the MD/PhD program at Duke University, studying chemokine receptor signaling and biased agonism under the mentorship of Sudar Rajagopal and Robert Lefkowitz. After completing an intern year in medicine, Jeffrey joined the Harvard Combined Dermatology Residency Program as part of an integrated physician-scientist pathway and where he cares for patients with complex skin diseases. He joined the Kruse Lab in 2022 and is studying noncanonical GPCR signaling pathways.